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Nanodiamonds as labels for integrated microscopy

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Integrated microscopy combines electron microscopy (EM) with light microscopy. However, conventional dyes bleach during the sample preparation for EM. NV centers in diamond, however, are protected within the lattice and thus remain fluorescent. As a result one can at the same time label cells optically and investigate the membrane structure. We can learn from this were diamond particles are within cells.

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